Articles

ARTHRITIS UPDATE! Maximizing Improvement Through Natural Combination Therapy
By Jose A. Rivera, M.D.


Back in October I reported on the benefits of sea cucumber (also known as Beche-de-Mer) for relief of various types of arthritic pain. I now have become aware of other natural compounds which dramatically complement the use of sea cucumber in holistic arthritis therapy. Although sea cucumber alleviated arthritic pain and helped reduce suffering overall, these benefits were primarily observed in early stages of arthritis and were generally classified as mild to moderate cases. Osteoarthritis (also known as degenerative arthritis, often correlated with injury or joint overuse) patients seem to respond rapidly to sea cucumber therapy, averaging noticed improvement often within days. However, in more severe cases such as rheumatoid arthritis (a debilitating and deforming type of arthritis involving a dysfunction of the immune system), the onset of benefits from sea cucumber supplementation often took much longer.

Unfortunately, typical "orthodox" medical treatment used for moderate to severe cases of arthritis commonly induce dangerous side-effects and may cause a "new batch of problems". Some of these side effects include bleeding ulcers, liver and kidney damage, elevated blood pressure, steroid induced diabetes and even weakening the immune system. Drugs potentially responsible for these serious ailments include non-steroidal anti-inflammatory drugs (such as aspirin and ibuprofen), steroids (oral and injectable cortisone), and gold compounds.

As mentioned earlier, oral supplementation of sea cucumber has been shown to be an effective, natural anti-inflammatory. These benefits are due to its contents of "joint lubricating" and "joint rebuilding" properties such as mucopolysaccaride and chrondroitin sulfate molecules. Others natural compounds demonstrated to enhanced the value of sea cucumber are several phyto-medicines ("phyto" meaning plant) commonly used in European medical practice. These herbal enhancers are the standardized extracts of Boswellia serrata, Curcuma longa, and Harpagophytum procumbens. Also, the "good" fat known as gamma-linolenic acid (G.L.A.) derived from the oil of the Borage plant, significantly increases the medicinal activity of sea cucumber.

Boswellia serrata (also known as Indian Frankincense) is a large branching tree found through-out India and Nepal. The medicinal properties occur in the gum resins or "guggals" of the plant. This unique material contains essential oils, terpenoids (bioflavanoid like molecules), and various polysaccharide (starch like) gums. Researchers in India extracted, isolated, and purified compounds from the gum resins known as boswellic acids. These plant acids have been found to be beneficial in suppressing the proliferating tissue found in inflamed areas of soft connective tissues such as joints, tendons, and ligaments. Studies have shown that boswellic acids may also prevent the breakdown of connective tissue. Due to these naturally occurring molecules (boswellic acids), Boswellia serrata had been shown in clinical trials to improve blood supply to the joints thus aiding in the healing process of arthritis.

Gamma linolenic acid (or G.L.A.) is a fatty acid critical to human biochemistry which naturally occurs in Borage oil. G.L.A. has been shown to play an important role in the regulation of the inflammatory process. The problem is that G.L.A. is very difficult (if not impossible) to obtain through the modern day diet and only has a few sources (i.e., evening primrose oil, black currant seed oil, borage oil, and mother's milk). Gram for gram, oil of borage is the most abundant. G.L.A. is also manufactured from specific essential fatty acids found in flax seeds, rapeseed (canola) and to a lesser extent, some fish body oils.

G.L.A. reduces swelling by converting into an anti-inflammatory chemical known as prostaglandin E1 (PGE1). This "good" prostaglandin has a "bad relative" called prostaglandin E2 (PGE2) which actually promotes swelling and pain. Studies have shown G.L.A. not only to minimize arthritic inflammation by increasing levels of PGE1, but also reduces the levels of the pro-inflammatory chemical PGE2.

Borage oil is much more than just a source of assets to the arthritis victim. Borage oil is rich in essential fatty acids often deficient in the diet. These essential fatty acids act as joint lubricants by promoting the production of synovial fluid and also aid in the integrity maintenance of tissues such as cartilage. Sadly enough, most people have diets rich in saturated and/or hydrogenated fats which only increase levels of PEG2 (the bad relative) and do nothing to elevate serum amounts of PEG1 (the good relative).

Curcuma longa (also known as Turmeric) is a staple in Indian cuisine and a major spice used in various curry recipes. Main portions of the plant used for cooking and medicinal purposes are the primary and secondary roots. These plant roots contain pigment chemicals (deep yellow in color) which have been found to inhibit biochemical pathways that contribute to the inflammatory process. These molecules, known as curcumminoids, also have anti-carcinogenic and anti-mutagenic properties, as well as potent antioxidant activity. The free radical scavenging/antioxidant effects of Curcuma longa aid in reducing pain and inflammation associated with trauma, as well as providing potent cell protection from future damage. From the kitchen cabinet to the medical pharmacy, Tumeric has not only added spice to our life, it has also added spice to our health!

Harpagophytum procumbens (also known as Devil's Claw) had been a standard in phyto-medicinal dispensed in Europe for a variety on inflammatory disorders for over twenty-five years. Even with the name Devil's Claw, the plant's popularity is ever increasing, perhaps due to the many scientific articles validating its use. The angelic properties of Devil's Claw include potent pain reduction and anti-inflammatory, thus making it a fine choice for the arthritis suffer.

As I previously mentioned, sea cucumber supplementation has significantly benefited my arthritic patients. As a physician who chooses to practice natural medicine, I am always looking for new research on natural compounds, especially herbal combinations scientifically proven to be effective. I truly believe that part of nature's healing wisdom is a harmony and synergism among natural agents. Lack of this "wisdom" is obvious when dealing with synthetic pharmaceutical drugs. Dangerous side-effects and even life threatening repercussions can be the result of multiple prescription drugs used at the same time. Sea cucumber, Boswellia serrata, Gamma linolenic acis, Curcuma longa, and Harpagophytum procumbens make a safe and highly effective combination of natural compounds for the individual suffering from moderate to severe forms of arthritis. Perhaps the only way to improve upon nature is through combining therapy...natural combination therapy!

Jose A. Rivera, M.D. is a board certified member of the International Federation of Holistic Medicine. He is a practicing physician specializing in nutrition, homeopathy, and botanical medicine. Dr. Rivera has lectures internationally regarding homeopathy and nutritional biochemistry.

Selected References

  1. Herbs That Heal-1994 Michael A. Weiner and Janet Weiner. Quantum Books.
  2. Fats That Heal, Fats That Kill-1993 Udo Erasmus. Alive Books.
  3. Physicians Desk Reference-1996 edition.
  4. Dr. Suzette M. Scarlatescu. Institute of Medicine and Pharmacy. Bucharest, Romania.